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Local Hyperthermia

Category(s): Oncology Medical

Local hyperthermia is capable of inducing temperature levels of up to 111.2°F in a designated area of the body. Moderate heating with temperature levels up to 104°F is used to induce a higher perfusion in the targeted area. This enhances the drug delivery into the tissue and therefore can be used as a general booster for a wide range of pharmacologic approaches. Intensive hyperthermia with temperatures ranging from 107.6°F to 111.2°F has a cytotoxic effect on the treated tissue. Cancer cells can be killed directly by this procedure. Additional effects are the enhancement of other cytotoxic procedures as cells face heavy stress and get more sensitive. Further on, affected cells start to express so called "Heat Shock Proteins" (HSP). These proteins are recognized by the immune system. Tumors hiding from the immune system can get "visible" again.


 


 
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